YMC-Triart Columns & Resins Copy
Learn more about the YMC-Triart series in person!
Pittcon 2025
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March 3 – 5 at Boston Convention & Exhibit Center
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Hybrid silica based columns ranging from UHPLC to prep

YMC-Triart phases are based on organic/inorganic hybrid particles that combine the high mechanical stability and efficiency of a silica-based packing material with the robust chemical stability of a polymer-based packing material. This versatile resin is produced using tightly controlled particle formation technology adapted from micro-reactor technology. The resulting uniform particle and pore size distributions as well as the smooth surface greatly contribute to excellent peak shape and separation reproducibility. In addition, YMC-Triart materials are highly resilient and robust when used at extreme pH, elevated temperature, and high pressure.
With high-level performance in a wide range of conditions, YMC-Triart is considered an ideal first choice column for method development.
Available Formats
Bonded YMC-Triart phases are available in 1.9 µm UHPLC as well as 3 and 5 µm analytical particle sizes, with several preparative options in 10 µm and higher.
All materials can be purchased in prepacked columns and guards as well as various quantities of bulk resin.
Column/guard sizes include*:
- Capillary (< 1 mm ID)
- Analytical (1.0 – 8.0 mm ID)
- Preparative (10 mm ID & above)
*Note: not all combinations of particle size, hardware material, and inner diameter are available. See individual product pages and column listings for specific offerings.
Hardware Materials
YMC-Triart columns can be packed in multiple types of hardware for even further flexibility.
- Standard stainless steel columns & guards
- YMC-Accura columns with bioinert coating
- PEEK-lined stainless steel columns
- High-pressure stainless steel columns
Visit the Hardware Specifications Page for more information about the different hardware options.
YMC-Triart Phase Comparison
Product Name | Stationary Phase | Bonding | End-capping | Particle Size (µm) | Pore Size (Å) | Carbon Content | pH Range | Typical Applications |
---|---|---|---|---|---|---|---|---|
C18 (USP L1) | Trifunctional | Multi-stage | 1.9, 3, 5 | 120 | 20% | 1-12 | acidic, neutral, basic compounds, medium polar compounds, peptides, oligonucleotides, small molecules, amino acids, APIs, sugars | |
C18 (USP L1) | Trifunctional | Multi-stage | 1.9, 3, 5 | 80 | 25% | 1-12 | stereoisomers and hydrophobic analytes, fatty acids | |
C18 (USP L1) | Trifunctional | Multi-stage | 1.9, 3, 5 | 300 | – | 1-12 | acidic, neutral, basic compounds | |
C8 (USP L7) | Trifunctional | Multi-stage | 1.9, 3, 5 | 120 | 17% | 1-12 | acidic, neutral, basic compounds | |
C4 (USP L26) | Trifunctional | Multi-stage | 1.9, 3, 5 | 300 | – | 1-10 | peptides, proteins, antibodies | |
phenylbutyl (USP L11) | Trifunctional | Multi-stage | 1.9, 3, 5 | 120 | 17% | 1-10 | aromatic compounds, pharmaceuticals, sweeteners | |
pentafluorophenyl (USP L43) | Trifunctional | None | 1.9, 3, 5 | 120 | 15% | 1-8 | aromatic stereoisomers, halogenated and polar compounds |
100% aqueous stable (no phase de-wetting for reversed phase)
Larger particle sizes available for direct scale-up
Normal Phase / HILIC
Product Name | Stationary Phase | Bonding | End-capping | Mode | Particle Size (µm) | Pore Size (Å) | Carbon Content | pH Range | Typical Applications |
---|---|---|---|---|---|---|---|---|---|
YMC-Triart Diol-HILIC | dihydroxypropyl (USP L20) | Trifunctional | None | HILIC | 1.9, 3, 5 | 120 | 12% | 2 – 10 | amino acids, water soluble vitamins, sugars, antibodies, proteins, peptides |
bare silica (USP L3) | None | None | Normal Phase / HILIC | 3, 5 | 120 | – | 2-8 | nucleic acids, amino acids, peptides, proteins, drugs, metabolites |
Larger particle sizes available for direct scale-up
YMC-Triart Phase Comparison
Product Name | Stationary Phase | Bonding | End-capping | Particle Size (µm) | Pore Size (Å) | Carbon Content | pH Range | Typical Applications |
---|---|---|---|---|---|---|---|---|
C18 (USP L1) | Trifunctional | Multi-stage | 1.9, 3, 5 | 120 | 20% | 1-12 | acidic, neutral, basic compounds, medium polar compounds, peptides, oligonucleotides, small molecules, amino acids, APIs, sugars | |
C18 (USP L1) | Trifunctional | Multi-stage | 1.9, 3, 5 | 80 | 25% | 1-12 | stereoisomers and hydrophobic analytes, fatty acids | |
C18 (USP L1) | Trifunctional | Multi-stage | 1.9, 3, 5 | 300 | – | 1-12 | acidic, neutral, basic compounds | |
C8 (USP L7) | Trifunctional | Multi-stage | 1.9, 3, 5 | 120 | 17% | 1-12 | acidic, neutral, basic compounds | |
C4 (USP L26) | Trifunctional | Multi-stage | 1.9, 3, 5 | 300 | – | 1-10 | peptides, proteins, antibodies | |
phenylbutyl (USP L11) | Trifunctional | Multi-stage | 1.9, 3, 5 | 120 | 17% | 1-10 | aromatic compounds, pharmaceuticals, sweeteners | |
pentafluorophenyl (USP L43) | Trifunctional | None | 1.9, 3, 5 | 120 | 15% | 1-8 | aromatic stereoisomers, halogenated and polar compounds |
100% aqueous stable (no phase de-wetting for reversed phase)
Larger particle sizes available for direct scale-up
Product Name | Stationary Phase | Bonding | End-capping | Mode | Particle Size (µm) | Pore Size (Å) | Carbon Content | pH Range | Typical Applications |
---|---|---|---|---|---|---|---|---|---|
YMC-Triart Diol-HILIC | dihydroxypropyl (USP L20) | Trifunctional | None | HILIC | 1.9, 3, 5 | 120 | 12% | 2 – 10 | amino acids, water soluble vitamins, sugars, antibodies, proteins, peptides |
bare silica (USP L3) | None | None | Normal Phase / HILIC | 3, 5 | 120 | – | 2-8 | nucleic acids, amino acids, peptides, proteins, drugs, metabolites |
Larger particle sizes available for direct scale-up