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Analytical: YMC BioPro HIC BF

Hydrophilic Polymer-based Hydrophobic Interaction Chromatography Column

YMC BioPro HIC BF is a hydrophobic interaction chromatography (HIC) column utilizing a butyl (C4) stationary phase bonded to non-porous hydrophilic polymer particles.  This HIC phase is specifically designed for fast, high resolution separations of proteins and biopharmaceutical drugs such as monoclonal antibodies (mAb’s), including drug-to-antibody ratio (DAR) analysis of antibody drug conjugates (ADC’s).


YMC BioPro HIC BF: Features & Benefits

Base Material: Hydrophilic Polymer (polymethacrylate)
Stationary Phase: Butyl (C4)
Particle Size: 4µm
Pore Size: N/A (non-porous)
Carbon Load: N/A
Endcapping: N/A
pH Range: 2-12
Temperature Range: 10-60⁰C
  • Butyl (C4) stationary phase bonded to hydrophilic polymer resin
  • Designed and optimized for antibodies, ADC’s, and other proteins
  • Optimized for analysis and lab-scale purification
  • High-throughput analysis made possible by rigid, non-porous particle
  • Excellent lot-to-lot reproducibility and durability



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