YMC Glass Columns


ECO Glass Columns

eco1 eco2ECO columns are competitively priced glass columns for almost all types of soft gel and low pressure (pressure limit 10 – 30 bar) liquid chromatography application. With a choice of one or two adjustable length plungers, it is available in two forms: AB (aqueous buffer) for use with aqueous buffers and cold room applications and SR (solvent resistant) for all forms of normal and reversed phase chromatography. A water-jacket option can be supplied on request.


  • Biocompatible
  • Solvent resistant
  • Easy to use
  • Low temperature application
  • 2 adjustable length plungers supplied on request
  • Compatible with any LC system
  • Water-jacket version available on request

Available Versions

Version Temperature Range (°C) Plunger Seal Frit
ECO AB (Aqueous Buffer) 4-40 POM Viton® O-ring Porous glass
ECO SR (Solvent Resistant) 16-40 PVDF Kalrez® O-ring Porous glass






Pressure limit: 10 – 30 bar
Wetted parts: borosilicate glass AB-Version: POM, sintered glass frit and Viton® seal SR-Version: PVDF, sintered glass frit and Kalrez® seal
Diameter: 10 mm, 15 mm, 25 mm, 50 mm, 70 mm and 80 mm
Length: 120 mm, 200 mm, 450 mm, 750 mm, 1000 mm
Connections: ID 10 – 25 mm: Two 1/4: – 28 fittings for 1/16″ capillaries ID 32 – 50 mm: Two 1/4″ – 28 fittings for 1/8″ capillaries
Height adjustment: Adjustable plunger provides up to 120mm bed height adjustment (2 adjustable plungers on request)


ECO Plus

ecoplus1 ecoplus2

ECOPLUS Glass Columns

ECOPLUS glass columns are multi-purpose for almost all types of liquid chromatography applications (pressure limit 30 – 80bar). They are available in two forms: AB (aqueous buffer) for aqueous buffer and cold room applications and SR (solvent resistant) for normal and reversed phase chromatography. Adjustable length plungers at both ends and a totally inert triple chevron sealing system (SR versions) support the complete spectrum of applications from classical normal phase and reversed phase chromatography right through to biochromatography. The Quick-Lock connection system makes it possible to open and seal the column simply and quickly.


  • Biocompatible
  • Universal application
  • Solvent resistant version
  • Low temperature version available with polyethylene plunger and EPDM sealing ring
  • Height adjustable plunger at both ends
  • Easy to use
  • Compatible with any LC system

Available versions

Version Temperature Range (°C) Plunger Seal Frit
ECOPLUS AB (Aqueous Buffer) 4-40 Polyethylene O-ring EDPM (ethylene polymer elastomer) Column ID 5 – 50 mm: Polyethylene (5 or 10 µm)
ECOPLUS SR (Solvent Resistant) 16-40 PTFE PTFE Triple chevron Column ID 5 – 15mm: sintered glassColumn ID 25 – 50mm: stainless steel








Pressure limit: 30 – 80 bar
Wetted parts: Borosilicate glass AB Version: Polyethylene and EPDM SR Version: PTFE and sintered glass or stainless steel
Diameter: 5 mm, 10 mm, 15 mm, 25 mm, 35 mm, 50 mmm
Length: 125 mm, 250 mm, 500 mm, further length are available on request
Connections: 1/4: – 28 fittings (four for 1/16″ and four for 1/8″ capillaries) The column is supplied with two M6 adaptors to allow direct connection to any LC-system.
Height adjustment: Multi-variable plunger at each end, each providing approximately 60mm bed height adjustment with Quick-Lock bayonet system (long plunber option approximately 120mm bed adjustment)








Pilot Columns

YMC Pilot Columns

pilotcolumnsPilot columns are designed for use in pilot and production scale applications with organic solvents (SR version) or aqueous buffers (AB version), which makes them suitable for all common methods in chromatography including normal phase, reversed phase or biochromatography. High precision CNC manufacturing of plungers and distribution plates provides outstanding flow distribution for a linear flow distribution profile. Precise and reliable bed height adjustment can be achieved by hand wheel adjusters on the plunger. The variety of mounting options includes a fixed stand, wheeled trolley, or direct attachment to plant. All materials are in compliance with FDA regulations; certification and full documentation are available for validation purposes on request.


  • Biocompatible
  • Solvent resistant version (optional)
  • Height adjustable plunger
  • Heating/cooling jackets available (optional)
  • Custom tailored for each application
  • Full stainless steel versions with extended pressure ratings available
  • Explosion proof and rotateable version and other customized features available on request
  • Full documentation for validation
  • Full service and support for custom designed columns


Pressure limit: 16 – 1 bar
Wetted parts: column tube: borosilicate glass 3.3 (precision bore tubing KPG®)
plunger: PVDF or stainless steel
seals: EDPM or Kalrez®
frits: PE or stainless steel (others on request)
Diameter: 100mm, 140mm, 200mm, 300mm (other sizes available by request)
Length: 500mm, 850mm (other sizes available by request)
Connections: SR Version: ¼” stainless steel tubing

AB Version: ¼” FEP tubing

Height adjustment: variable plunger allows for manual height adjustment











YMC PilotPLUS Columns


YMC PilotPLUS is the new standard for your pilot scale applications. The column is compatible with common BioLC separation modes (IEX, SEC, Affinity, IMAC, HIC, MMC) and aqueous conditions. Due to the bioinert environment and minimal dead volumes, the column is perfectly suitable for the separation of biomolecules (e.g. proteins, oligonucleotides or nucleic acids).


  • Fully biocompatible
  • Removable column body allows for easy unpacking and cleaning
  • Excellent column performance
  • Bubble-free piston insertion due to unique drain function
  • Permanent seal with tool-free maintenance


Pressure limit: 16-5 bar
Wetted parts: Borosilicate glass 3.3, FEP, PE, PTFE, PEEK, 75
Fluoroprene XP41 blue
column tube: borosilicate glass 3.3
seals: 75 Fluoroprene XP41 blue
frits: PE
Diameter: 70mm, 100mm, 140mm, 200mm
Length: 500mm, 850mm
Connections: FEP tubing ¼” OD