YMC Pilot Glass Columns

Glass Columns for Pilot and Production Scale

Pilot columns are designed for use in pilot and production scale applications with organic solvents (SR version) or aqueous buffers (AB version), making them suitable for all common methods of chromatography including normal-phase, reversed-phase, or biochromatography. High precision CNC manufacturing of plungers and distribution plates provides outstanding flow distribution for a linear flow distribution profile. Precise and reliable bed height adjustment can be achieved by hand wheel adjusters on the plunger. The variety of mounting options includes a fixed stand, wheeled trolley, or direct attachment to plant. All materials are in compliance with FDA regulations; certification and full documentation are available for validation purposes on request.

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Features & Benefits

Pressure limit: Varies by column body:
1 – 16 bar for glass
50 bar for stainless steel
Wetted parts: column tube: borosilicate glass 3.3 (precision bore tubing KPG®), acrylic glass or stainless steel
piston: PTFE, PVDF or stainless steel
seals: EDPM, Viton® or Kalrez®
frits: PE or stainless steel (others on request)
Diameter: 60mm, 100mm, 140mm, 200mm, 300mm, 450mm, 600mm
*other sizes available by request
Length: 500mm, 850mm
*other sizes available by request
Connections: 1/4″ tubing (stainless steel – SR version or polyethylene – AB version) or larger, depending on diameter
Height adjustment: continuously variable plunger providing up to 300mm bed height adjustment


  • Biocompatible
  • Solvent resistant and aqueous buffer versions available
  • Height adjustable plunger
  • Heating/cooling jackets available (optional)
  • Custom tailored for each application
  • Full stainless steel versions with extended pressure ratings available
  • Explosion-proof and rotatable version, as well as other customized features available on request
  • Full documentation for validation
  • Full service and support for custom designed columns