Hybrid UHPLC and HPLC Columns and Media: YMC-Triart Diol-HILIC

There is a lot of interest in HILIC (hydrophilic interaction liquid chromatography), particularly among LC/MS users.  Mobile phases used in HILIC separations are generally “LC/MS friendly.”

YMC-Triart Diol-HILIC begins with an organic/inorganic hybrid base particle with excellent durability and usability across a wide pH range.  It is then synthesized with a dihydroxypropyl (Diol) group.  The resulting material is ideal for the separation of polar compounds that are not retained well using other methods.

The diol group is a neutral functional group that exhibits low nonspecific adsorption.  YMC-Triart Diol-HILIC displays excellent reproducibility.  These columns also exhibit increased stability under alkaline conditions as compared to silica based diol columns.  YMC-Triart Diol-HILIC is rated with a pH range of 2-10.  Available particle sizes are 1.9µm, 3µm, and 5µm.

For more information on YMC-Triart Diol-HILIC, please visit our website:

https://www.ymcamerica.com/columns/special/hilic.htm