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Size exclusion chromatography (SEC) column for mAb separations.

YMC-SEC MAB is a silica based size exclusion chromatography column specifically designed for antibody separations.

Optimized base material design and surface modification provide superior separation of antibody monomers and their aggregates/fragments with very low nonspecific adsorption. This is ideal for the quality control assessment of antibody drugs.

YMC-SEC MAB exhibits excellent resolution and peak shape over a wide molecular weight range of 10 kDa to 700 kDa.


  • Excellent resolution and peak shapes
  • Optimized for separating aggregates and fragments of mAbs
  • Suitable for SEC analysis of antibody drug conjugates (ADCs) using organic-containing mobile phases


Typical applications include: antibodies, aggregates, fragments, large proteins


Stationary Phase dihydroxypropyl (USP L20, L59)
Mode SEC
Particle Size 3 µm
Pore Size 250 Å
pH Range 5-7.5
Temperature Limit 40 °C

Available Formats

Analytical Resin (3 µm)

  • Prepacked columns
    • Capillary (< 1 mm ID)
    • Analytical (4.6 & 8.0 mm ID)

LC Columns & Accessories

ProductPhase / TypeSeparation Mode(s)Pore SizesParticle SizespH RangeAvailable FormatsLink to Order
YMC-SEC MABDihydroxypropylSize Exclusion (SEC)250 Å3 µm5 - 7.5Analytical (1 - 8 mm ID)Capillary (< 1 mm ID)

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