Skip to main content

Chromatography of Biotherapeuticals – Analyzing and Purifying Peptides and Oligonucleotides

This webinar will highlight how advanced ultra-high-performance liquid chromatography (UHPLC) strategies, carefully selected stationary phases, and bioinert hardware can significantly improve the analysis and purification of peptides and oligonucleotides by enhancing resolution, recovery, and sensitivity. Using the GLP-1 receptor agonist tirzepatide as a representative example, attendees will gain practical insights into chromatographic method development, from analyte assessment and mobile phase selection to stationary phase screening and final method optimization.  The webinar will also demonstrate the impact of bioinert hardware on chromatographic performance and show how tailored chromatographic approaches can support reliable characterization, improved reproducibility, and robust quality control of modern biotherapeutics.  In addition, the webinar will discuss Twin-Column Chromatography techniques and present an oligonucleotide purification case study using MCSGP.

Presented by Daniel Eßer, PhD, (YMC Euorpe) and J Preston, PhD (YMC America), this webinar is hosted by LCGC on Tuesday, Jun 23 at 11:00 AM Eastern Time.  Click here to learn more and register.

Posted on June 2, 2026.

Related Posts

September 4, 2026

YMC America Brings U.S.-Supplied ASME U-Stamped DAC Columns to Pharmaceutical Manufacturers

YMC America will be the First U.S.-Based Supplier of ASME U-Stamped DAC Columns. The company’s DAC columns support pharmaceutical and biopharmaceutical customers from process development through commercial production. Systems are used in laboratory, pilot, and production-scale chromatography applications, including purification processes for peptides, oligonucleotides, and small-molecule APIs.

September 10, 2026

Analytical Technologies for Therapeutic Peptides

Therapeutic peptides are an emerging class of active pharmaceutical ingredients that, together with other classes of bioproducts, have been attracting considerable attention due to their unique advantages. Their structure is based on well-defined amino acid sequences that may or may not contain structural modifications, resulting in molecules that generally range from 500 to 5000 Da. Currently, many examples can be used as medicines related to hormones, growth factors, neurotransmitters, among others.

September 9, 2026

Tecnologias Analíticas para Peptídeos Terapêuticos- Portuguese

Os peptídeos terapêuticos são uma classe emergente de insumos farmacêuticos ativos que, juntamente com outras classes de bioprodutos, vêm despertando grande interesse devido às suas vantagens únicas.

Designed and developed by