Dynamic Axial Compression Columns (DACs)
YMC provides dynamic axial compression columns suited for laboratory, pilot, and industrial scale. These automated self-packing columns allow for an easy, cost-effective refill of packing material that results in a column bed yielding superior durability and reproducibility. Our DAD series operates using a downward-driving piston that maintains constant pressure on the bed during use and also simplifies packing and unpacking.
Highlights
- ASME U‑Stamped DAC Columns (inner diameter 300-1000)
- Cost-effectiveness increased with self-packing
- Superior column performance, durability, and reproducibility provided by constant pressurization (Axial Compression Technology)
- Optional slurry container permits hygienic automated packing procedures
- Simple and safe operation
- Compatible with IQ/OQ and explosion-proof operation
YMC America designs its DAC columns in accordance with ASME Section VIII, Division 1 and manufactures them under an active ASME Certificate of Authorization (U‑Stamp and R‑Stamp). Columns (inner diameter 300-1000) are assembled, inspected, pressure‑tested, and U‑stamped at our Devens, Massachusetts facility in the United States under YMC’s ASME‑approved quality control program, with full U‑1A documentation and National Board registration. While key components are sourced globally, all ASME‑required pressure‑boundary fabrication, inspection, and certification are performed in our United States facility. This makes YMC America the only provider offering US-stamped DAC columns built for the demands of peptide, oligonucleotide, and small‑molecule API production.

Overview

This data shows repacking data obtained by using a 50 mm ID DAC column.
After repacking the column seven times, “plates/m” and “Tf” values are still as good as in the initial state.

Specifications
All columns are 700 mm in length with a 100 – 400 mm bed length
| Model Number | Maximum Pressure (MPa) | Inner Diameter (mm) | Slurry Container Model Number2 | Detailed Specs Sheet |
|---|---|---|---|---|
| DAD-50 | 10 | 50 | SC-2-20 | DAD50 |
| DAD-100 | 10 | 100 | SC-10-20SA | DAD100 |
| DAD-150 | 10 | 150 | SC-22-20 | DAD150 |
| DAD-200 | 10 | 200 | SC-30-20 | DAD200 |
| DAD-300 | 10 | 300 | SC-80-45 | DAD300 |
| DAD-4501 | 71 | 450 | SC-140-45 | DAD450 |
| DAD-600 | 7 | 600 | SC-300-135 | DAD600 |
| DAD-800 | 7 | 800 | Inquire | DAD800 |
| DAD-1000 | 5 | 1000 | Inquire | DAD1000 |
2 Slurry containers are optional.

Request a Quote
For more information or to request a quote, reach out to your local YMC rep or fill out our contact form.

