The task of separating two enantiomers (identical structure but mirror image) can result in life-saving therapies. The separation of a racemic mixture of two isomers into their constituent enantiomers is the process of chiral separation. Although chiral molecules (enantiomers) have identical physical properties, the chiral nature of the molecules exhibits pronounced differences in pharmacology and toxicology activities within biological environments. Different practices have been developed for chiral separation at both analytical and preparative scales. YMC has a range of products to facilitate the efficient separation of enantiomers.
YMC has developed high-performance packed materials, packed columns, and preparative HPLC devices corresponding to various scales, from microanalysis to large preparations, as products for chromatography, mainly for achiral separations. In the field of chiral technology, we are attempting to reduce the cost of chiral separation by proposing optimal column selection, high-efficiency preparative methods, and purification contract services based on our past achievements and know-how.
Examples of YMC chiral offerings:
Cost-Effective Chiral Separation by Preparative HPLC
Development of a Novel Immobilized Type Polysaccharide Chiral Stationary Phase for Enantiomeric Separations
Development of an Improved Amylose-based Chiral Stationary Phase with Excellent Preparative Performance
Highly efficient purification of enantiomers using polysaccharide type chiral stationary phases and continuous purification technology
Fast Method Screening for Separation of Enantiomers in HPLC and SFC Utilizing Novel Polysaccharides Type Chiral Stationary Phases Based on Small Particles
YMC Chiral Separation ART Cellulose-SZ
YMC Insight Center – A Virtual Tour
YMC Insight Center CEO Perspective on Lab Services
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