Lab Services

YMC Insight Services give you immediate access to experts

YMC Insight Services enable you to leverage the expertise of a YMC laboratory in your region to accelerate your development. Our labs are equipped with state-of-the-art instrumentation and staffed by scientists who truly understand development methods and applications for understanding your product. We can help you bring your product development goals to fruition.

Our services include:

  • Scale-down of analytical HPLC methods to UHPLC
  • Impurity amplification and identification
  • Continuous purification via multi-column chromatography
  • Scale-up of analytical to preparative separations for purification
  • Column screening to find the best resin match for your process or analysis
  • Rugged and robust LC method development for validation
  • Method troubleshooting and improvement
  • Generation of a new method or optimization of an existing method
  • Development services for both small and large molecules, batch, or continuous processes

YMC labs can be found in the following locations:

Note: Some labs may not offer all services noted

Continuous (multi-column) process application development

Seeking to investigate the cost savings and productivity gains of moving from batch to continuous development? Our experts in multi-column processes for small and large molecules offer discovery services in our labs or your facility to deliver reliable insights quickly and economically.

  • Purification and process development
  • Process modeling
  • Isolation of product-related impurities
  • Feasibility studies
  • On-site rentals
  • Workshops

Contract purification

YMC offers contract purification services for high-value-added substances, API. We can optimize methods, depending on the objective and required purity, and perform preparative purification at our Japan facility using preparative LC systems and packing materials, developed and produced in-house—often using a cost-saving approach.

Separation and purification using chromatography gives you access to cutting-edge technology while saving time and cost. At YMC, our purification service gives you the full benefit of our accumulated experience, know-how, and proven equipment. For full-scale production, YMC operates a GMP-compliant facility located in Japan.

For more on CMO and contract purification, click here.

Liquid chromatography laboratory services

YMC America offers fee-based HPLC application and method development on a wide range of instrumentation, including the following:

  • Agilent 1200 Series HPLC with PDA Detection
  • Waters ACQUITY UPLC with PDA Detection
  • YMC LC-Forte/R semi-preparative LC (up to 50mL/min flowrate, UV and IR Detection)
  • Advion expression CMS (≤1200Da mass range)

We can customize methods to the analyte of interest and provide a robust method with your final goal(s) in mind, including:

  • Scale-down of analytical HPLC methods to UHPLC
  • Scale-up of analytical to preparative separations for purification
  • Column screening to find the best stationary phase match for your analysis
  • Rugged and robust LC method development for validation
  • Method troubleshooting and improvement

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