Dynamic Axial Compression Columns DAD/DAU

Product Information

YMC provides dynamic axial compression columns suited for various separation scales such as laboratory-, pilot- and industrial-scale. They are automated self packing columns that allow for an easy, cost-effective refill of packing material that results in a column bed yielding superior durability and reproducibility. DAD series which can be operated easy unpacking with downward cylinder driving direction, DAU series which are compact design with upward cylinder driving direction, and rotatable custom-designed DAR series are available.

DAD

DAC

DAU

HIGHLIGHTS

Cost-effective provided by self-packing
Superior column performance, durability and reproducibility provided by constant pressurization (Axial Compression Technology)
Optional slurry container permits hygiene automated packing procedures
High performance packing provided by simple and safety operation
Compatible with IQ/OQ and explosion-proof operation

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Features

Prevention of voids by constant pressurization
Optional slurry container permits automated packing procedures
Column performance
Seamless scale-up

Prevention of voids by constant pressurization

In packing operation of axially compression columns, pressurizing by cylinder followed by loading slurry into columns can create homogenous packed bed. Packed bed pressurized by cylinder realizes high performance columns which are high densely and homogenously packed. Prevention of voids by constant pressurization also realizes long column life as a result of improvement of durability. (Axial Compression Technology)

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Optional slurry container permits automated packing procedures

The slurry container provides excellent distribution of packing material and allows for a “homogenous” slurry that can be automatically loaded into the DAU / DAD column by simply switching a valve. Throughout the operation from slurry preparation to filling slurry, safety and hygiene can be achieved.

Column performance

The data on the right hand side shows repacking data obtained by using a 50 mmI.D. DAU column (DAU-50). After 7 times repacking, plates/m and Tf are still as good as the initial state.

Column performance

Seamless scale-up

The chromatography on the right hand side are a scale-up example from an analytical 4.6 mmI.D. column to a 50 mmI.D. DAU column. This indicates that the very similar separation pattern of analytical scale is also reproducible at the preparative scale.

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Column :YMC-Pack C8 (S-5 μm, 200 Å)
150 X 4.6 mmI.D.
Flow rate : 0.8 mL/min

Column : YMC*GEL C8 (S-10 μm, 200 Å)
150 X 50 mmI.D.
Eluent : A) water/TFA (100/0.1)
B) acetonitrile/TFA (100/0.1)
25-60%B (0-20 min)
Flow rate : 100 mL/min
Temperature : 37℃
Detection : UV at 220 nm

Specification

DAU series : Driving direction of cylinder is upward. ( Catalog Download )

	DAU-50	DAU-100	DAU-150	DAU-200	DAU-300	DAU-450	DAU-600
Maximum Pressure (MPa)	10	10	10	10	10	7	7
Inner diameter (mm)	50	100	150	200	300	450	600
Column length (mm)	700	700	700	700	700	700	700
Column bed length (mm)	100 – 400	100 – 400	100 – 400	100 – 400	100 – 400	100 – 400	100 – 400
*Slurry container volume (L)**	2	10	22	30	60	140	250

DAD series : Driving direction of cylinder is downward. ( Catalog Download )

	DAD-50	DAD-100	DAD-150	DAD-200	DAD-300	DAD-450	DAD-600	DAD-800	DAD-1000
Maximum Pressure (MPa)	10	10	10	10	10	7	7	7	7
Inner diameter (mm)	50	100	150	200	300	450	600	800	1000
Column length (mm)	850	850	850	850	850	850	850	850	850
Column bed length (mm)	100 – 500	100 – 500	100 – 500	100 – 500	100 – 500	100 – 500	100 – 500	100 – 500	100 – 500
*Slurry container volume (L)**	2	10	22	30	80	160	300	600	1200

*Option

Instructional Video

Packing & Testing the YMC 10cm Dynamic Axial Compression (DAU) Column