Award-winning, innovative technologies that save time and cost

The downstream operation in biopharma production is dedicated to the precise separation and purification of target molecules (proteins) to strict regulatory standards. This process requires multiple steps involving several chromatographic and filtration devices and consumables. YMC has advanced the conventional unit processes through innovation that begins at the lab scale and extends through GMP scale production of these large molecule therapeutics. Continuous chromatography is only one of our disruptive technologies leading the industry to more cost-effective and efficient ways to produce these life-saving drugs.

We work with clients that are the leading producers of:

  • mAbs
  • Recombinant proteins
  • RNA
  • dsDNA
  • Oligo & peptides
  • Transgenics
  • Vaccines
  • ADCs

Downstream done right

At every turn, we aim to make things easy for you:

YMC is steeped in industry best practices and routinely develops new designs, solutions, and equipment to advance processing and control trends such as batch processing and the move from batch to continuous processes. Our Contichrom TWIN LPLC is an industry-first innovation, leading the evolution to continuous capture chromatography (and so much more).

We understand the sensitive nature of proteins and use thoughtful engineering design and pumps known for GMP compliance and low shear design. We know how to integrate multi-unit/multi-process solutions for maximum throughput and operational ease. (Integrating buffer in-line dilution right into a chromatography system is a YMC innovation that saves significant space and cost.)

Often, a single system of our design has the capacity range of multiple competitive units, delivering the footprint savings that manufacturing managers crave.

We know your molecule is unique. Where we shine is when we work together to customize a system to your needs, so you get exactly what you want. We’re friendly and flexible—small enough to listen but big enough to deliver innovation.

Digitally enhanced controls that are user adaptable

Our innovation in digital control of the industry-leading metering pump and user-adaptable control systems provides ultimate control and yield during the purification of valuable bioproducts. Our proprietary design methods commonly deliver accuracy previously only attainable in analytical instruments. With gradient accuracy well below +/-0.5%, YMC Process Technologies has been making enormous strides in the hardware and now enhances our offering with systems with columns, methods development, and resins from YMC.

A complete family of tools and services

We draw from YMC’s nearly 40-year history in supplying critical separations and purification technologies to the world’s largest firms. YMC never leaves you with supplier “finger-pointing” frustrations.

YMC gives our customers a full range of tools and services to draw from, including:

  • Methods development
  • Feasibility studies
  • Columns
  • Resin / gels / media
  • Chromatography systems—batch and continuous (multi-column)
  • Membrane TFF systems
  • Dilution systems
  • Support services
  • Global yet local

We welcome the chance to lower your total cost of ownership (TCO), speed your time-to-market, reduce your line’s footprint, and improve product consistency and integrity of your biopharmaceutical processes. And with a global network of specialists from Singapore to Tokyo, Zurich to Dublin, and Boston to San Diego, you’re always close to a local YMC contact.

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