Optimizing Liquid Chromatography for Vitamin Analysis
Vitamins play a critical role in human health, serving as precursors to vital coenzymes, supporting metabolic pathways, and offering widespread benefits across the pharmaceutical, nutraceutical, and cosmetic industries. However, analyzing water-soluble vitamins such as the B-complex group and Vitamin C, presents unique challenges for analytical chemists.
Because these essential compounds are highly polar, achieving robust separation requires specialized chromatographic strategies.
A recent technical brief from YMC highlights how choosing the right stationary phase and chemistry can dramatically improve method development for complex multivitamin panels.
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Happy Retirement, John! Related Posts
July 16, 2026
Making Peptide Purification Green without Forfeiting Productivity.
While green solvents like ethanol and DMC are better for the planet, they typically suffer from lower chromatographic resolution in traditional setups. This has resulted in a trade-off of choosing sustainability, or choosing high yield.
The whitepaper Counter-Current Chromatography Enables Use of Green Solvents for Productive Peptide Purification Processes shows how using Multi-column Counter-current Solvent Gradient Purification (MCSGP) can overcome the inefficiencies of eco-friendly mobile phases.
June 18, 2026
Happy Retirement, John!
Today, we are celebrating John Heffernan, who is officially stepping into retirement after 16 years with YMC America.
John’s journey with us actually began back when we were known as Integrated Process Technologies, long before we transitioned to YMC America. Over the years, John has worn many hats, from Project Manager to Estimating Manager, Engineering Manager, and ultimately Director of Business Development.
June 2, 2026
Chromatography of Biotherapeuticals – Analyzing and Purifying Peptides and Oligonucleotides
This webinar will highlight how advanced ultra-high-performance liquid chromatography (UHPLC) strategies, carefully selected stationary phases, and bioinert hardware can significantly improve the analysis and purification of peptides and oligonucleotides.
