YMC-BioPro HIC
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Columns specifically designed for drug-to-antibody conjugates (ADCs) and antibodies.
YMC-BioPro HIC HT / BF are hydrophobic interaction chromatography (HIC) columns that utilize a butyl (C4) stationary phase bonded to non-porous hydrophilic polymer particles.
BioPro HIC HT offers higher resolution than conventional HIC columns and is the first choice for ADCs or mAbs.
BioPro HIC BF columns show a stronger retention and can therefore be used for the separation of low hydrophobic proteins or for the analysis of oxidized mAbs.
YMC-BioPro HIC columns are available in 4.6 mm ID.
Specifications
BioPro HIC HT | BioPro HIC BF | |
---|---|---|
Base Particle | hydrophilic polymer (polymethacrylate) | hydrophilic polymer (polymethacrylate) |
Particle Size (µm) | 2.3 | 4 |
Pore | non-porous | non-porous |
Functional Group | butyl | butyl |
pH Range | 2-12 | 2-12 |
Pressure Limit | 40 MPa (5,800 psi) | 20 MPa (2,900 psi) |
Temperature Range | 10 – 60° C | 10 – 60° C |