Used to determine the presence and/or the concentration of analyte(s) in a sample, analytical chromatography is a cornerstone of any industry reliant on chemistry. In analytical chromatography, a stationary phase is bonded to the support particles, such as silica packed inside a column. The outcome of moving a mobile phase through the stationary phase produces a chromatogram as a visual output of the chromatograph. Typically, the mobile phase is pumped through the packed bed at pressures between 50 and 350 bar.
Peaks representing the various constituents in the mobile phase offer the chromatographer a “picture” of what the solution contains and the probable concentration of the individual molecules present. As opposed to preparative chromatography where the objective is to purify a useful amount (milligrams or grams) of a single compound, analytical chromatography is used to identify individual components for purposes of quality control, discovery, or other qualitative analyses. The eluents in analytical chromatography may not even be collected or retained.
Experts in the field of analytical chromatography have long considered YMC a premier supplier of phases and columns for use in the analysis of nearly any liquid chemical solution. YMC provides HPLC columns, analytical columns, ion exchange chromatography columns/packing materials for purification of biopharmaceuticals, and chiral chromatography columns/packing materials, which can separate a wide range of compounds.
UHPLC Guard Cartridge Columns for YMC-Triart
Normal Phase Products and Applications (catalog excerpt)
Presentation: Analytical to prep scale tools for the purification of bio/pharmaceuticals
Purification of Anti-Body Conjugates using the Contichrom CUBE FPLC System
Enrichment of a product-related compounds by N-Rich
N-Rich – Automated enrichment and purification of minor compounds from complex matrices
The N-Rich Process Principle
Improvement in productivity of the method development for the drug analyses by using a novel hybrid reversed phase column
Characterization and evaluation of a novel C18 column based on organic/inorganic hybrid silica for HPLC and UHPLC
Characteristics of Diol column and retention behavior of hydrophilic compounds in Hydrophilic Interaction Chromatography (HILIC)
YMC Solutions for Bioseparations
N-Rich: A tool for efficient isolation of minor compounds from complex matrices
YMC Insight Center – A Virtual Tour
YMC - What We Do
Webinar: Analytical to prep scale tools for the purification of bio/pharmaceuticals
Use our extensive Applications Search page to mine a dynamically growing collection of over 350 YMC-produced application notes.
The data can be searched by any combination of several variables, including sample classification, compound name (including partial names), and column parameters.
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