Webinar on Continuous Countercurrent Chromatography

Twin-column continuous countercurrent chromatography is an excellent technique for achieving high yield and high purity in the manufacturing scale purification of peptide and oligo therapeutics.

YMC ChromaCon is pleased to offer a webinar on the topic. The webinar presents the concept of the technique, recent results of oligonucleotide and peptide purification by countercurrent chromatography, and key economic aspects for scale-up.

The YMC/ChromaCon technology employs MCSGP (Multicolumn Countercurrent Solvent Gradient Purification) — a chromatography process that uses two columns of the same type with internal recycling and automatic re-separation of overlapping side-fractions to elute and recover product of high purity at a high yield.

Because impurities partially overlap with the peak at preparative load conditions, traditional batch LC purification can be optimized for yield or purity, but not both. MCSGP is able to maximize both of these variables without requiring a second purification step.

The webinar is presented by Thomas Müller-Späth, Ph.D. Späth is CTO at YMC ChromaCon AG. He holds over ten patents and is author/co-author of over 30 articles and book chapters on continuous chromatography for biopharmaceuticals and downstream processing.

You can view the webinar here.