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YMC-Pack PVA-Sil

Polyvinyl alcohol functionalized silica.

YMC-Pack PVA-Sil is prepared from a 5µm, 120 Å silica support which is bonded with a monomolecular polymer coating of vinyl alcohol. The polymerized PVA completely covers both external and internal surfaces of the silica support, protecting it against aggressive, high pH buffers and solvents.

YMC-Pack PVA-Sil is an excellent alternative to silica gel or other polar bonded phases used in normal phase chromatography. In many situations, it exhibits better performance characteristics with a unique selectivity, and can often resolve compounds that behave poorly on bare silica. The alcohol functionality present on PVA-Sil is better suited for troublesome compounds, such as organic bases, than the acidic silanols present in unbonded silica. Since PVA-Sil is a bonded stationary phase, it can be washed with solvents of any polarity from hexane to water, without altering the surface activity. Therefore; selectivity, retention, and resolution are reproducible regardless of the column’s previous history.


  • Bonded phase alternative to silica for normal-phase applications
  • Vinyl alcohol polymerized silica support
  • Consistent surface activity, unaffected by water
  • Excellent for packed column supercritical fluid chromatography


Typical applications include: phospholipid classes


Stationary Phase polyvinyl alcohol
(USP L24)
Bonding Monomeric
Particle Size 5 µm
Pore Size 120 Å
pH Range 2 – 9.5
Temperature Upper Limit 50 °C
Temperature Recommended Range 20 – 40 °C

Available Formats

  • Prepacked columns & guards
    • Capillary (< 1 mm ID)
    • Analytical (1.0 – 8.0 mm ID)
    • Preparative (10 mm ID & above)
  • Bulk resin

LC Columns & Accessories

ProductPhase / TypeSeparation Mode(s)Pore SizesParticle SizespH RangeAvailable FormatsLink to Order
YMC-Pack PVA-SilPolyvinyl AlcoholNormal Phase120 Å5 µm2 - 9.5Analytical (1 - 8 mm ID)Capillary (< 1 mm ID)Preparative (10 mm ID & above)

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