Hydrosphere C18
Provides superior separation of hydrophilic compounds.
Hydrosphere C18 is based on highly inert, ultra-pure, pH neutral silica, and is designed to maintain a hydrophilic surface for superior separation of hydrophilic compounds. Minimal metal content and very low concentrations of residual silanols make this an ideal phase for the analysis of basic pharmaceuticals and chelating compounds, even under LC-MS conditions such as separation in non-phosphate buffered systems. In addition, the ability to separate polar compounds under highly aqueous mobile phase conditions without loss in retention, plate counts, and peak performance greatly enhances the versatility of Hydrosphere C18.
Characteristics
- Made with highly inert, ultrapure, pH neutral silica
- Hydrophilic C18 surface for enhanced polar selectivity
- Extremely rigorous physical and chemical specifications
- Suitable for conventional reversed phase and highly aqueous applications
- Suitable for pharmaceutical method development
Applications
Typical applications include: strong polar compounds, water-soluble vitamins
Specifications
| Stationary Phase | C18 (USP L1) |
|---|---|
| Bonding | Monomeric |
| Particle Size | 2, 3, 5 µm |
| Pore Size | 120 Å |
| Carbon Content | 12% |
| pH Range | 2 – 8 |
| Temperature Upper Limit | 50 °C |
| Temperature Recommended Range | 20 – 40 °C |
Available Formats
- Prepacked columns & guards
- Capillary (< 1 mm ID)
- Analytical (1.0 – 8.0 mm ID)
- Preparative (10 mm ID & above)
LC Columns & Accessories
| Product | Phase / Type | Separation Mode(s) | Pore Sizes | Particle Sizes | pH Range | Available Formats | Link to Order |
|---|---|---|---|---|---|---|---|
| Hydrosphere C18 | C18 | Reversed Phase | 120 Å | 3 µm5 µm2 µm | 2 - 8 | Analytical (1 - 8 mm ID)Capillary (< 1 mm ID)Preparative (10 mm ID & above) |
