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YMC Hydrosphere C18

Ultra-pure Silica-based C18

The YMC Pro Family is based on a silica with an extremely low metal content.  Low metal content suppresses polar interactions, as metal impurities cause silanol groups to become more acidic.  This ensures YMC Pro Family phases provide excellent resolution for a wide range of compounds, especially basic pharmaceuticals.  To minimize the unwanted interactions between residual silanols and the sample molecules that are responsible for asymmetric peaks, YMC utilizes a proprietary, highly effective endcapping process.  Important for every chromatographer: YMC ensures that the physical properties, such as particle size, pore size, and metal content, are extremely reproducible from lot to lot.

Specifications

YMC Hydrosphere C18: Features & Benefits

Specifications
Base Material: Ultra-pure Silica
Stationary Phase: C18 (USP L1)
Particle Size: 2µm, 3µm, 5µm
Pore Size: 120Å
Carbon Load: 12%
Bonding: Monomeric
Endcapping: Yes
pH Range: 2-8

The combination of ultra pure silica and unique selectivity leads to a stationary phase that fulfills the relevant requirements of HPLC users.  Minimal metal content and very low concentrations of residual silanols make this an ideal phase for the analysis of basic pharmaceuticals and chelating compounds, even under LC-MS conditions (ex. separation in non-phosphate buffered systems.)  In addition, the possibility to separate polar compounds under highly aqueous mobile phase conditions without loss in retention, plate counts, and peak performance greatly enhances the versatility of Hydrosphere C18.  These characteristics will allow Hydrosphere C18 to be used for a wide range of applications of compounds with polar functional groups.

  • Based on highly inert, ultra-pure, pH neutral silica
  • Hydrophilic C18 surface for enhanced polar selectivity
  • Extremely rigorous physical and chemical specifications
  • Suitable for conventional reversed phase and highly aqueous applications
  • Pharmaceutical method development

Applications

Applications

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Product List

Product Table

Please select the desired particle size to view a list of products.

2µm

Particle Size Pore Size Column I.D. (mm) Column Length (mm) Part Number PriceQuantity
2µm120Å2.0 30 HS12S02-0302WT $673.00
2µm120Å2.0 50 HS12S02-0502WT $720.00
2µm120Å2.0 75 HS12S02-L502WT $720.00
2µm120Å2.0 100 HS12S02-1002WT $720.00
2µm120Å2.0 150 HS12S02-1502WT $752.00
2µm120Å 3.0 30 HS12S02-0303WT $720.00
2µm120Å 3.0 50 HS12S02-0503WT $720.00
2µm120Å 3.0 75 HS12S02-L503WT $720.00
2µm120Å 3.0 100 HS12S02-1003WT $720.00
2µm120Å 3.0 150 HS12S02-1503WT $752.00
2µm120Å 4.6 50 HS12S02-0546WT $720.00

3µm

Particle Size Pore Size Column I.D. (mm) Column Length (mm) Part Number PriceQuantity
3µm120Å1.0 35 HS12S03-H501WT $482.00
3µm120Å1.0 50 HS12S03-0501WT $482.00
3µm120Å1.0 100 HS12S03-1001WT $505.00
3µm120Å 1.5 35 HS12S03-H5P5WT $482.00
3µm120Å 1.5 50 HS12S03-05P5WT $482.00
3µm120Å 1.5 100 HS12S03-10P5WT $505.00
3µm120Å 2.0 35 HS12S03-H502WT $418.00
3µm120Å 2.0 50 HS12S03-0502WT $418.00
3µm120Å 2.0 75 HS12S03-L502WT $542.00
3µm120Å 2.0 100 HS12S03-1002WT $542.00
3µm120Å 2.0 150 HS12S03-1502WT $651.00
3µm120Å 2.1 50 HS12S03-05Q1WT $418.00
3µm120Å 3.0 50 HS12S03-0503WT $418.00
3µm120Å 3.0 100 HS12S03-1003WT $563.00
3µm120Å 3.0 150 HS12S03-1503WT $701.00
3µm120Å 4.6 35 HS12S03-H546WT $418.00
3µm120Å 4.6 50 HS12S03-0546WT $418.00
3µm120Å 4.6 75 HS12S03-L546WT $563.00
3µm120Å 4.6 100 HS12S03-1046WT $563.00
3µm120Å 4.6 150 HS12S03-1546WT $736.00
3µm120Å 4.6 250 HS12S03-2546WT $1,002.00
3µm120Å 6.0 50 HS12S03-0506WT $700.00
3µm120Å 6.0 75 HS12S03-L506WT $730.00
3µm120Å 6.0 100 HS12S03-1006WT $775.00

5µm

Particle Size Pore Size Column I.D. (mm) Column Length (mm) Part Number PriceQuantity
5µm120Å1.0 150 HS12S05-1501WT $556.00
5µm120Å1.0 250 HS12S05-2501WT $636.00
5µm120Å 1.5 150 HS12S05-15P5WT $556.00
5µm120Å 1.5 250 HS12S05-25P5WT $636.00
5µm120Å 2.0 30 HS12S05-0302WT $372.00
5µm120Å 2.0 35 HS12S05-H502WT $386.00
5µm120Å 2.0 50 HS12S05-0502WT $386.00
5µm120Å 2.0 75 HS12S05-L502WT $517.00
5µm120Å 2.0 100 HS12S05-1002WT $517.00
5µm120Å 2.0 150 HS12S05-1502WT $598.00
5µm120Å 2.0 250 HS12S05-2502WT $673.00
5µm120Å 3.0 50 HS12S05-0503WT $418.00
5µm120Å 3.0 75 HS12S05-L503WT $547.00
5µm120Å 3.0 100 HS12S05-1003WT $547.00
5µm120Å 3.0 150 HS12S05-1503WT $651.00
5µm120Å 3.0 250 HS12S05-2503WT $736.00
5µm120Å 4.6 50 HS12S05-0546WT $418.00
5µm120Å 4.6 75 HS12S05-L546WT $591.00
5µm120Å 4.6 100 HS12S05-1046WT $547.00
5µm120Å 4.6 150 HS12S05-1546WT $673.00
5µm120Å 4.6 250 HS12S05-2546WT $774.00
5µm120Å 6.0 150 HS12S05-1506WT $818.00
5µm120Å 6.0 250 HS12S05-2506WT $846.00

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