Different Separation Characteristics from Bare Silica Gel

YMC-Pack Diol-NP shows typical normal-phase retention behavior when used with low-polarity mobile phases due to hydroxyl groups on the surface of the stationary phase acting as polar groups.  Diol-NP is as widely applicable to normal-phase separations as standard silica gel, but is useful in cases where separation optimization is difficult to achieve with silica.  In addition, it can also be used in HILIC-mode with organic/water mobile phases