Hybrid Silica ODS
YMC-Triart Bio C4 is a novel, organic/inorganic hybrid silica derivatized with C4 (L26 USP designation) based on wide-pore (300Å) particles. This new stationary phase is designed for HPLC and UHPLC separations of proteins and oligonucleotides, and is particularly useful for intact antibody analyses run at high temperatures. Triart Bio C4 is well-suited for high-sensitivity analysis using mass spec-friendly mobile phases containing formic acid and/or TFA. As with all Triart products, chromatographers enjoy wide temperature and pH ranges (up to 90°C at pH 1-7, and 50°C at pH 7-10), allowing these parameters to be used as tools for optimizing separation conditions, without having to worry about stationary phase durability.
Triart Hybrid Advantages
The core material for all of the YMC-Triart products – the particle – is inspired by YMC’s flow chemistry technology. Inherent in YMC’s process is a high level of temperature and particle formation control. As a result, Triart particles are consistent, reproducible, and scalable across many particle sizes. The hybrid Triart particles produce a material that is highly resilient and robust when used at extreme pH and elevated temperature. In addition, these particles are very stable under mechanical stress such as high pressure.