Leading CMO purchases multiple GMP scale twin-column units

Today, we are celebrating John Heffernan, who is officially stepping into retirement after 16 years with YMC America. John’s journey with us actually began back when we were known as Integrated Process Technologies, long before we transitioned to YMC America. Over the years, John has worn many hats, from Project Manager to Estimating Manager, Engineering Manager, and ultimately Director of Business Development.

This webinar will highlight how advanced ultra-high-performance liquid chromatography (UHPLC) strategies, carefully selected stationary phases, and bioinert hardware can significantly improve the analysis and purification of peptides and oligonucleotides.

Evaluating 5' capping efficiency is a critical quality attribute in therapeutic mRNA manufacturing, directly impacting translation efficiency and transcript stability. However, separating structurally similar capped, partially capped, and uncapped species differing by just a single nucleotide remains a significant chromatographic challenge.