News, Page 1
August 5, 2026
Maximizing Oligonucleotide Yield Without Sacrificing Purity
Purifying Antisense Oligonucleotides (ASOs) via traditional single-column batch chromatography often leaves downstream teams facing a frustrating trade-off: sacrifice valuable target product in impure side-fractions, or settle for lower overall purity.
August 3, 2026
Portuguese – Vitaminas Complexo B
As vitaminas são nutrientes essenciais para a manutenção da saúde e, por isso, produtos que as contêm em sua formulação exigem um controle de qualidade rigoroso. Esse processo é fundamental para garantir que a quantidade de vitaminas presente no produto esteja de acordo com as especificações estabelecidas, assegurando qualidade e confiabilidade ao consumidor. Clique no link abaixo e confira como suplementar o seu laboratório para a análise de vitaminas do complexo B.
July 30, 2026
Two-Step RP Purification of Tirzepatide
Scaling Up Tirzepatide Purification: From 20% Crude to >99% Purity
With the surge in demand for GLP-1 receptor agonists, efficient and scalable purification strategies for complex lipopeptides like Tirzepatide have never been more critical.
July 29, 2026
Portuguese – Análise de PFAS: Desafios, Aplicações e Soluções para LC-MS
PFAS são amplamente reconhecidas por suas propriedades excepcionais e inúmeras aplicações industriais. No entanto, um número crescente de evidências aponta para riscos potenciais tanto ao meio ambiente quanto à saúde humana por meio da exposição à água e aos alimentos contaminados. Descubra nosso artigo mais recente sobre PFAS e veja como as colunas YMC para (U)HPLC podem contribuir para análises confiáveis de PFAS.
July 29, 2026
PFAS Analysis: Challenges, Applications, and Reliable LC-MS Solutions
PFAS are widely recognized for their exceptional properties and countless industrial applications. However, increasing evidence points to potential risks for both the environment and human health through exposure to contaminated water and food. Discover our latest article on PFAS and explore how YMC (U)HPLC columns can support reliable PFAS analysis.
July 29, 2026
Spanish – Análisis de PFAS: Desafíos, Aplicaciones y Soluciones para un Análisis Confiable por LC-MS
Los PFAS son ampliamente reconocidos por sus propiedades excepcionales y sus innumerables aplicaciones industriales. Sin embargo, cada vez existen más evidencias que señalan posibles riesgos tanto para el medio ambiente como para la salud humana debido a la exposición a agua y alimentos contaminados. Descubra nuestro artículo más reciente sobre PFAS y conozca cómo las columnas YMC para (U)HPLC pueden contribuir a un análisis confiable de estos compuestos.
July 16, 2026
Making Peptide Purification Green without Forfeiting Productivity.
While green solvents like ethanol and DMC are better for the planet, they typically suffer from lower chromatographic resolution in traditional setups. This has resulted in a trade-off of choosing sustainability, or choosing high yield.
The whitepaper Counter-Current Chromatography Enables Use of Green Solvents for Productive Peptide Purification Processes shows how using Multi-column Counter-current Solvent Gradient Purification (MCSGP) can overcome the inefficiencies of eco-friendly mobile phases.
July 8, 2026
Optimizing Liquid Chromatography for Vitamin Analysis
Vitamins play a critical role in human health, serving as precursors to vital coenzymes, supporting metabolic pathways, and offering widespread benefits across the pharmaceutical, nutraceutical, and cosmetic industries. However, analyzing water-soluble vitamins such as the B-complex group and Vitamin C, presents unique challenges for analytical chemists.
June 18, 2026
Happy Retirement, John!
Today, we are celebrating John Heffernan, who is officially stepping into retirement after 16 years with YMC America.
John’s journey with us actually began back when we were known as Integrated Process Technologies, long before we transitioned to YMC America. Over the years, John has worn many hats, from Project Manager to Estimating Manager, Engineering Manager, and ultimately Director of Business Development.
June 2, 2026
Chromatography of Biotherapeuticals – Analyzing and Purifying Peptides and Oligonucleotides
This webinar will highlight how advanced ultra-high-performance liquid chromatography (UHPLC) strategies, carefully selected stationary phases, and bioinert hardware can significantly improve the analysis and purification of peptides and oligonucleotides.
May 21, 2026
Breaking Down mRNA Capping Efficiency with High-Resolution IP-RP LC
Evaluating 5' capping efficiency is a critical quality attribute in therapeutic mRNA manufacturing, directly impacting translation efficiency and transcript stability. However, separating structurally similar capped, partially capped, and uncapped species differing by just a single nucleotide remains a significant chromatographic challenge.
May 7, 2026
Revolutionizing CRISPR Applications: High-Resolution sgRNA Analysis
Ensuring the quality of single guide RNA (sgRNA) is a major hurdle in CRISPR-Cas genome editing. Because these molecules are large (~100mer) and prone to complex secondary structures, separating them from nearly identical impurities requires precision. Our latest application note
