Biosynthesis in the field of therapeutic compounds typically refers to building through a physical synthesis process, portions of RNA or DNA molecules (oligonucleotides). These molecules are constructed using amino acids (reagents) that are sequenced into a larger molecular construct (oligonucleotide) using a system of precision pumps and valves in an inert gas environment. These systems typically use proprietary controls to maintain the precise sequence and monitor the process.
YMC has supplied custom biosynthesis systems to the world’s largest oligonucleotide companies. YMC engineering and controls expertise in the field of GMP compliant processes enables users to get a system engineered to their proprietary process. These systems are complemented by YMC’s array of HPLC, cleavage and deprotect systems, and tangential flow (TFF/UF) units that serve to purify the solutions produced with YMC engineered biosynthesis systems.
Oligonucleotides: Current Trends and Innovative Applications in the Synthesis, Characterization, and Purification
Use our extensive Applications Search page to mine a dynamically growing collection of over 350 YMC-produced application notes.
The data can be searched by any combination of several variables, including sample classification, compound name (including partial names), and column parameters.
ACCESS APPLICATION SEARCH
For more information on products and services from YMC, YMC ChromaCon, or just to say hello, get in touch with us by clicking on the button below.
Columns, Guards and Accessories are only available for purchase online in North America or through our distributors.
To purchase consumables outside North America, please find your local distributor.
For YMC systems’ sales outside of North America and Europe, find your regional office contact information here.