There is a lot of interest in HILIC (hydrophilic interaction liquid chromatography), particularly among LC/MS users. Mobile phases used in HILIC separations are generally “LC/MS friendly.”
YMC-Triart Diol-HILIC begins with an organic/inorganic hybrid base particle with excellent durability and usability across a wide pH range. It is then synthesized with a dihydroxypropyl (Diol) group. The resulting material is ideal for the separation of polar compounds that are not retained well using other methods.
The diol group is a neutral functional group that exhibits low nonspecific adsorption. YMC-Triart Diol-HILIC displays excellent reproducibility. These columns also exhibit increased stability under alkaline conditions as compared to silica based diol columns. YMC-Triart Diol-HILIC is rated with a pH range of 2-10. Available particle sizes are 1.9µm, 3µm, and 5µm.
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