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Continuous Purification: CaptureSMB

CaptureSMB resources

The CaptureSMB Process Principle

Maximizing the efficiency of affinity capture steps

CaptureSMB for the continuous purification of mAbs with high productivity and load

CaptureSMB is a twin-column periodic countercurrent (PCC) process used for the continuous purification of monoclonal antibodies (mAbs) and antibody fragments using affinity resins such as Protein A and Protein L.

Capture SMB; Twin-column chromatography—how it works, economics, and applications

This 25-minute presentation (plus 15-minute Q&A) walks through how a twin-column chromatography system works, both at the bench and production scale.

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