Preparative Columns

YMC has a proven history of direct scale-up from analytical and semi-prep columns to prep scale units. Preparative columns are available in empty or pre-packed formats in a variety of configurations.  Find more information about our different options below. To request a quote, please contact our office or reach out to your local rep.


YMC-Actus® Prepacked Prep Columns

  • Standard column IDs: 20, 30, and 50 mm
  • Available in 50 – 250 mm lengths
  • YMC stationary phases: YMC-Triart, CHIRAL ART, and reversed phase classics


YMC-Actus SP

  • Spring-assisted axial compression technology eliminates voids
  • 50 – 450 mm ID columns available, 250 mm length
  • Can be packed and QC tested prior to shipping with YMC or other manufacturers’ resins
  • Ideal alternative to DAC columns when lab space or packing capabilities are limited


Glass Columns

  • Lab scale configurations from 5 – 80 mm ID
  • Production scale configurations from 70 – 300 mm ID
  • Aqueous buffer and solvent resistant versions available


Dynamic Axial Compression (DAC) Columns

  • Automated self-packing columns for lab, pilot, and industrial scale
  • Constant pressurization prevents voids in packing material
  • 50 – 1000 mm ID configurations available
  • Optional slurry container for added hygiene and safety


Preparative scale-up calculator

Let our scale-up calculator assist you in scaling up the chromatographic parameters such as flow rate or the amount of packing material. The use of the calculator is very simple: You only have to fill in the fields with the corresponding values and, after the parameters have been scaled up, you can also select the appropriate YMC (semi) preparative columns on our overview page. Benefit from the expertise of our scale-up calculator.


Application Search

Use our extensive Applications Search page to mine a dynamically growing collection of over 350 YMC-produced application notes.

The data can be searched by any combination of several variables, including sample classification, compound name (including partial names), and column parameters.

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