Normal-Phase Alternative to Silica
YMC-Pack PVA-Sil, which possesses a polyvinyl alcohol (PVA) surface chemistry, is an excellent alternative to silica gel or other polar bonded phases which are used in normal-phase chromatography. In many situations, it exhibits better performance characteristics with a unique selectivity, and can often resolve compounds that behave poorly on bare silica. The alcohol functionality present on PVA-Sil is better suited for troublesome compounds, such as organic bases, that acidic silanols present in unbonded silica. Since PVA-Sil is a bonded stationary phase, it can be washed with solvents of any polarity from hexane to water, without altering the surface activity. Therefore; selectivity, retention, and resolution are reproducible regardless of the column’s previous history. This is not true of bare silica, which easily becomes completely deactivated following the introduction of even a small quantity of water.
Polyvinyl Alcohol Functionalized Silica
YMC-Pack PVA-Sil is prepared from a 5µm, 120Å silica support which is bonded with a monomolecular polymer coating of vinyl alcohol. The polymerized PVA completely covers both external and internal surfaces of the silica support, protecting it against aggressive, high pH buffers, and solvents.
Columns, Guards and Accessories are only available for purchase online in North America or through our distributors.
To purchase consumables outside North America, please find your local distributor.
For YMC systems’ sales outside of North America and Europe, find your regional office contact information here.