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J’sphere ODS-M80

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YMC America will make a donation to St Jude Children’s Hospital for every prepacked column sold.

4 µm ODS with Three Levels of Hydrophobicity

The J’sphere series of columns consists of three kinds of ODS made from the same silica gel base, each with a different ligand coverage.. The 4 µm, 80 Å silica support provides outstanding chromatographic efficiency, while the high surface area material (500 m2/g) offers exceptional interaction with analytes. This combination provides excellent peak symmetry across all J’sphere products.

The variations in ligand coverage produce three columns with different hydrophobicity, hydrogen bonding capacity, and steric selectivity for tertiary structures. Because of this, J’sphere can be used with confidence to identify structural differences of solutes and to improve the efficiency of separation optimization.


  • Choice of three levels of hydrophobicity
  • Average over 100,000 plates/meter
  • Inert, reproducible support
  • Excellent peak symmetry with basic molecules


Typical applications include: positional isomers and complexing agents

Phase Comparison

The following chart is an overview of the three materials in this series.

Product Name Stationary Phase Bonding End Capping Mode Particle Size (µm) Pore Size (Å) Carbon Content pH Range Typical Applications
J’sphere ODS-H80 C18
(USP L1) Polymeric Yes Reversed phase 4 80 22 1-9 Remarkably high hydrophobicity and surface coverage with excellent chemical resistance to acid and alkali
J’sphere ODS-M80 C18
(USP L1) Monomeric Yes Reversed phase 4 80 14 2-7.5 inert, efficient phase with moderate hydrophobicity and hydrogen bonding capacity
J’sphere ODS-L80 C18
(USP L1) Polymeric Yes Reversed phase 4 80 9 2-7.5 Extremely low hydrophobicity with unique selectivity due to hydrogen bonding capacity

Available Formats

  • Prepacked columns & guards
    • Capillary (< 1 mm ID)
    • Analytical (1.0 – 8.0 mm ID)
    • Preparative (10 mm ID & above)

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