Ultra-pure Silica-based C18
The YMC Pro Family is based on a silica with an extremely low metal content. Low metal content suppresses polar interactions, as metal impurities cause silanol groups to become more acidic. This ensures YMC Pro Family phases provide excellent resolution for a wide range of compounds, especially basic pharmaceuticals. To minimize the unwanted interactions between residual silanols and the sample molecules that are responsible for asymmetric peaks, YMC utilizes a proprietary, highly effective endcapping process. Important for every chromatographer: YMC ensures that the physical properties, such as particle size, pore size, and metal content, are extremely reproducible from lot to lot. YMC Hydrosphere C18 consists of a hydrophilic C18 surface exhibiting enhanced polar selectivity, allowing for separation of polar compounds under high aqueous mobile phase conditions without loss of retention, plate count, or peak performance. This enhanced versatility allows Hydrosphere C18 to be used in a wide range of applications for compounds with polar functional groups.