Most Polar Reversed-Phase Column
In reversed-phase mode, cyano columns are the most polar and least retentive of all reversed-phase packings. Extremely hydrophobic compounds which do not elute in standard C18 and C8 packings can be retained using typical reversed-phase eluents. In addition, the unique nitrile chemistry provides different selectivity from both phenyl and standard aliphatic (C18, C8, and C4) reversed-phase packings. Large pore-size 300Å packing materials are also available for the analysis of biomolecules in order to utilize this unique selectivity.
Useful in Both Reversed-Phase and Normal-Phase Modes
YMC-Pack CN can be used in both reversed-phase and normal-phase modes since it utilizes a cyanopropyl group of medium polarity bonded to the stationary phase. Hydrophobicity is relatively low for a reversed-phase packing material, exhibiting different selectivity from C18 due to π electrons from the cyano group. In reversed-phase mode, YMC-Pack CN is useful for shortening analysis time when retention is too long using C18, or when different selectivity is required to optimize the separation.
Please select the desired particle size to view a list of products.
10mm & 20mm ID
30mm & 50mm ID
No products of this type are available at this time. Please check again later.
Columns, Guards and Accessories are only available for purchase online in North America or through our distributors.
To purchase consumables outside North America, please find your local distributor.
For YMC systems’ sales outside of North America and Europe, find your regional office contact information here.