Ultra-pure Silica-based C18
The YMC Pro Family is based on a silica with an extremely low metal content. Low metal content suppresses polar interactions, as metal impurities cause silanol groups to become more acidic. This ensures YMC Pro Family phases provide excellent resolution for a wide range of compounds, especially basic pharmaceuticals. To minimize the unwanted interactions between residual silanols and the sample molecules that are responsible for asymmetric peaks, YMC utilizes a proprietary, highly effective endcapping process. Important for every chromatographer: YMC ensures that the physical properties, such as particle size, pore size, and metal content, are extremely reproducible from lot to lot. YMC-Pack Pro C18 columns consist of highly purified silica gel, a high-coverage C18 bonding (16% carbon load), and a unique endcapping procedure utilizing Lewis acid/Lewis base chemistry.