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Micro/Capillary: YMC- Pack CN (Cyano)

Most Polar Reversed-Phase Column

In reversed-phase mode, cyano columns are the most polar and least retentive of all reversed-phase packings.  Extremely hydrophobic compounds which do not elute in standard C18 and C8 packings can be retained using typical reversed-phase eluents.  In addition, the unique nitrile chemistry provides different selectivity from both phenyl and standard aliphatic (C18, C8, and C4) reversed-phase packings.  Large pore-size 300Å packing materials are also available for the analysis of biomolecules in order to utilize this unique selectivity.


YMC- Pack CN (Cyano): Features & Benefits

Base Material: Silica
Stationary Phase: Cyano (USP L10)
Particle Size: 3µm, 5µm
Pore Size: 120Å, 300Å
Carbon Load: 7%, 3%
Bonding: Monomeric
Endcapping: Yes
pH Range: 2-7.5

Useful in Both Reversed-Phase and Normal-Phase Modes

YMC-Pack CN can be used in both reversed-phase and normal-phase modes since it utilizes a cyanopropyl group of medium polarity bonded to the stationary phase.  Hydrophobicity is relatively low for a reversed-phase packing material, exhibiting different selectivity from C18 due to π electrons from the cyano group.  In reversed-phase mode, YMC-Pack CN is useful for shortening analysis time when retention is too long using C18, or when different selectivity is required to optimize the separation.

  • Useful in both normal- and reversed-phase applications
  • Stable, high coverage, monomerically-bonded phase
  • Fully endcapped
  • Alternative selectivity
  • Available in 300Å for biomolecule analysis

Product List

Product Table

Please select the desired particle size to view a list of products.


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