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YMCBasic Analytical Guard Columns

Designed for Analysis of Basic Compounds

YMCbasic is a unique reversed-phase column designed for analysis of pharmaceuticals and basic compounds.  This stationary phase utilizes a novel silica synthesis and state-of-the-art silane bonding to create a column which gives true reversed-phase character, high resolution, and excellent peak shape that is typically difficult to obtain when analyzing basic analytes.

Neutral Silica Plus Maximum Bonding Coverage

The silica support used in YMCbasic is prepared by an advanced synthetic process which yields a chromatographic material with proprietary pore size and neutral silanols which minimizes interactions with both basic and acidic compounds.  The stationary phase is a monomeric bonding of several different alkyl silanes with chain lengths of C8 and smaller.

Guard Cartridges

Analytical Guard Cartridges: Features & Benefits

YMC’s Guard Column Cartridge Systems for HPLC accept cartridges of 1.0, 2.1, 3.0, or 4.0mm inner diameters – in either 10mm or 20mm lengths.  Cartridges are available with a comprehensive selection including all stationary phase chemistries offered by YMC, ensuring compatibility between the guard column and the analytical column.   Assembly is tool-free, simplifying cartridge replacement.

YMC Guard Column Cartridges require the use of a holder, P/N: XPGCHP1 for 10mm length and P/N: XPGCHP2 for 20mm length.

Product Table

Please select the desired particle size to view a list of products.


Holder required

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Holder required

[vartable id=”8099″]


Holder required

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Sold Individually

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Guard Columns

Analytical Guard Columns: Features & Benefits

YMC’s Guard Columns for HPLC are available in 4.0mm and 5.0mm diameters and come in 10mm lengths.  These guard columns are available with a comprehensive stationary phase selection offered by YMC, ensuring compatibility between the guard column and the analytical column.  Unlike our guard cartridge columns, these guard columns do not require a holder, but do require a small jumper made from either stainless steel or PEEK tubing in order to connect them to the inlet of the analytical column.

Product Table

No holder required

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