YMC*GEL/YMC*GEL HG/YMC-Omega

Product Information

YMC*GEL for preparative HPLC has various available functional groups, such as reversed-phase and normal-phase, and also various particle sizes from 3 μm with high-resolution to 150 μm for open column chromatography. YMC*GEL is able to work for a long period of time without particle breakage, as it uses high-density and high-strength silica gel. YMC*GEL/YMC*GEL HG packing materials are widely used both domestically and internationally.

Highlights

Packing materials with various functional groups and particle sizes are available
High density and high mechanical strength silica gel (YMC*GEL HG)
Suited for large-scale purification by using dynamic axial compression column
Packing materials for flash chromatography and open column chromatography are available

Features

Excellent mechanical stability (YMC*GEL HG)
Suitable for separation of peptides
Purification of EPA-EE (YMC-Omega)
Lineup

Excellent mechanical stability (YMC*GEL HG)

The high mechanical stability of YMC*GEL HG is demonstrated by means of repeated measurements with a dynamic axial compression column (DAC). Even after more than 10 repacking cycles with the same material, the pressure does not increase. The absence of fines is proven by a constant backpressure.

ymcgel

Packing conditions
Column size： 100×50 mmI.D., Packing pressure : 6.5 MPa

Test conditions
Eluent ： methanol/water（85/15）, Flow rate : 50 mL/min

Suitable for separation of peptides

YMC*GEL/YMC*GEL HG are available with various functional groups and also with wide pores. Therefore, this material is suitable for the preparation of peptides, such as insulin and proteins. YMC*GEL HG can make scaling up from analytical scale to preparative scale easy, as it has the same performance as that of YMC-Pack.

Purification of EPA-EE (YMC-Omega)

Optimization of the flow rate and sample loading for high yield was performed by using a preliminary column with 10 mmI.D., and the preparative column was scaled up by using dynamic axial compression columns with 200 mmI.D. Although using two times the linear flow rate slightly decreases the yield per preparation, the productivity can be increased because the preparation time per preparation is halved and the productivity per unit time increases 180%.

ymcgel3

Column ： YMC-Omega (10 μm)
Eluent ： methanol
Temperature ： ambient
Detector ： UV at 210 nm
Sample ： 70% EPA-EE

Lineup

YMCGEL/YMCGEL HG

Product	Particle size （μm)	Pore size (Å)	Characteristics
ODS-A	3, 5	120, 200, 300	Standard ODS
ODS-A-HG	10, 15, 20, 50	120, 200, 300	Standard ODS
ODS-AM	3, 5	120	outstanding lot-to-lot reproducibility
ODS-AQ	3, 5	120, 200, 300	Superiour separation of hydrophilic compounds
ODS-AQ-HG	10, 15, 20, 50	120, 200, 300	Superiour separation of hydrophilic compounds
C8	3, 5	120, 200, 300	Useful for separation of relatively highly hydrophobic compounds Useful for separation of proteins and peptides
C₈-HG	10, 15, 20, 50	120, 200, 300
C4	3, 5	120, 200, 300	Stationary phase with low hydrophobicity Useful for separation of proteins and peptides
C₄-HG	10, 15, 20, 50	120, 200, 300
TMS	3, 5	120, 200, 300	Reverse phased packing material with the lowest hydrophobicity
TMS-HG	10, 15, 20, 50	120, 200, 300
Ph(Phenyl)	3, 5	120, 200, 300	Different separation characteristics from C18
Ph-HG	10, 15, 20, 50	120, 200, 300	Different separation characteristics from C18
CN	3, 5	120, 200, 300	The medium polarity of the functional group allows selectable normal-phase and reversed-phase separation modes
CN-HG	10, 15, 20, 50	120, 200, 300
YMCbasic	3, 5, 10	–	Superior separation of basic compounds and peptides
SIL	3, 5	120, 200, 300	Standard of normal-phase packing material
SIL-HG	10, 15, 20, 50	120, 200, 300	Standard of normal-phase packing material
Diol	5	120, 200, 300	Useful for gel filtration or normal-phase applications
Diol-HG	10, 15, 20, 50	120, 200, 300	Useful for gel filtration or normal-phase applications
NH₂	5	120, 200, 300	Chemically bonded with aminopropyl groups
NH₂-HG	10, 15, 20, 50	120, 200, 300	Chemically bonded with aminopropyl groups

YMC-Omega

Product	Particle size （μm)	Pore size (Å)	Characteristics
Omega	10, 20, 50	–	Superior separation of omega-fatty acids

Packing materials for Flash chromatography

Product	Particle size （μm)	Characteristics
SIL	irregular 50 μm spherical 25 μm	Low priced and easy to use packing material
NH2		Suitable for basic compounds
Diol		Different selectivity from bare silica gel
ODS		Suitable for organic solvent partially insoluble sample

Packing materials for Open column chromatography

Product	Particle size （μm)	Pore size (Å)
ODS-A	75, 150	60,120
SIL	75, 150	120

Product List

HIGH RESOLUTION PACKING MATERIALS (3 µm, 5 µm）

Packing material	Particle size (μm)	Pore size (Å)	Product code
ODS-A	3	120	AA12S03
	5	120	AA12S05
	5	300	AA30S05
ODS-AM	3	120	AM12S03
ODS-AM	5	120	AM12S05
ODS-AQ	3	120	AQ12S03
ODS-AQ	5	120	AQ12S05
C₈	5	120	OC12S05
C₈	5	300	OC30S05
C₄	5	120	BU12S05
C₄	5	300	BU30S05
TMS	5	120	TM12S05
Ph	5	120	PH12S05
CN	5	120	CN12S05
CN	5	300	CN30S05
SIL	5	60	SL06S05
SIL	5	120	SL12S05
NH₂	5	120	NH12S05

Bulk packing materials (10-50 μm)

Packing material	Particle size (μm)	Pore size (Å)	Product code
ODS-A-HG	10	120	AAG12S11
	15		AAG12S16
	20		AAG12S21
	50		AAG12S50
ODS-AQ-HG	10	120	AQG12S11
	15		AQG12S16
	20		AQG12S21
	50		AQG12S50
SIL-HG	10	120	SLG12S11
	15		SLG12S16
	20		SLG12S21
	50		SLG12S50

For flash chromatography (irregular, 50 μm）

Packing material	Product code
SIL	SLK08I52
NH2	NHK08I52
Diol	DLK08I52
ODS	AAK08I52

For flash chromatography (spherical, 25 μm）

Packing material	Product code
SIL	SLF08S25
NH2	NHF08S25
Diol	DLF08S25
ODS	AAF08S25

* Prease inquiry Price.

For open column chromatography （spherical, 75, 150 μm）

Packing material	Particle size (μm)	Pore size (Å)	Product code
ODS-A	75	120	AA12S75
ODS-A	150	120	AA12SA5
SIL	75	120	SL12S75
SIL	150	120	SL12SA5