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YMC*GEL/YMC*GEL HG/YMC-Omega

Product Information

YMC*GEL for preparative HPLC has various available functional groups, such as reversed-phase and normal-phase, and also various particle sizes from 3 μm with high-resolution to 150 μm for open column chromatography. YMC*GEL is able to work for a long period of time without particle breakage, as it uses high-density and high-strength silica gel. YMC*GEL/YMC*GEL HG packing materials are widely used both domestically and internationally.

Highlights

  • Packing materials with various functional groups and particle sizes are available
  • High density and high mechanical strength silica gel (YMC*GEL HG)
  • Suited for large-scale purification by using dynamic axial compression column
  • Packing materials for flash chromatography and open column chromatography are available

Excellent mechanical stability (YMC*GEL HG)

The high mechanical stability of YMC*GEL HG is demonstrated by means of repeated measurements with a dynamic axial compression column (DAC). Even after more than 10 repacking cycles with the same material, the pressure does not increase. The absence of fines is proven by a constant backpressure.

ymcgel

Packing conditions
Column size: 100×50 mmI.D., Packing pressure : 6.5 MPa

Test conditions
Eluent : methanol/water(85/15), Flow rate : 50 mL/min


Suitable for separation of peptides

YMC*GEL/YMC*GEL HG are available with various functional groups and also with wide pores. Therefore, this material is suitable for the preparation of peptides, such as insulin and proteins. YMC*GEL HG can make scaling up from analytical scale to preparative scale easy, as it has the same performance as that of YMC-Pack.

Capture


Purification of EPA-EE (YMC-Omega)

Optimization of the flow rate and sample loading for high yield was performed by using a preliminary column with 10 mmI.D., and the preparative column was scaled up by using dynamic axial compression columns with 200 mmI.D. Although using two times the linear flow rate slightly decreases the yield per preparation, the productivity can be increased because the preparation time per preparation is halved and the productivity per unit time increases 180%.

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Column : YMC-Omega (10 μm)
Eluent : methanol
Temperature : ambient
Detector : UV at 210 nm
Sample : 70% EPA-EE


Lineup

YMC*GEL/YMC*GEL HG

Product Particle size (μm) Pore size (Å) Characteristics
ODS-A 3, 5 120, 200, 300
  • Standard ODS
ODS-A-HG 10, 15, 20, 50
ODS-AM 3, 5 120
  • outstanding lot-to-lot reproducibility
ODS-AQ 3, 5 120, 200, 300
  • Superiour separation of hydrophilic compounds
ODS-AQ-HG 10, 15, 20, 50
C8 3, 5 120, 200, 300
  • Useful for separation of relatively highly hydrophobic compounds
  • Useful for separation of proteins and peptides
C8-HG 10, 15, 20, 50
C4 3, 5 120, 200, 300
  • Stationary phase with low hydrophobicity
  • Useful for separation of proteins and peptides
C4-HG 10, 15, 20, 50
TMS 3, 5 120, 200, 300
  • Reverse phased packing material with the lowest hydrophobicity
TMS-HG 10, 15, 20, 50
Ph(Phenyl) 3, 5 120, 200, 300
  • Different separation characteristics from C18
Ph-HG 10, 15, 20, 50
CN 3, 5 120, 200, 300
  • The medium polarity of the functional group allows selectable normal-phase and reversed-phase separation modes
CN-HG 10, 15, 20, 50
YMCbasic 3, 5, 10
  • Superior separation of basic compounds and peptides
SIL 3, 5 120, 200, 300
  • Standard of normal-phase packing material
SIL-HG 10, 15, 20, 50
Diol 5 120, 200, 300
  • Useful for gel filtration or normal-phase applications
Diol-HG 10, 15, 20, 50
NH2 5 120, 200, 300
  • Chemically bonded with aminopropyl groups
NH2-HG 10, 15, 20, 50

YMC-Omega

Product Particle size (μm) Pore size (Å) Characteristics
Omega 10, 20, 50
  • Superior separation of omega-fatty acids

Packing materials for Flash chromatography

Product Particle size (μm) Characteristics
SIL irregular 50 μm
spherical 25 μm
  • Low priced and easy to use packing material
NH2
  • Suitable for basic compounds
Diol
  • Different selectivity from bare silica gel
ODS
  • Suitable for organic solvent partially insoluble sample

Packing materials for Open column chromatography

Product Particle size (μm) Pore size (Å)
ODS-A 75, 150 60,120
SIL 75, 150 120

Product List

HIGH RESOLUTION PACKING MATERIALS (3 µm, 5 µm)

Packing material Particle size (μm) Pore size (Å) Product code
ODS-A 3 120 AA12S03
5 AA12S05
5 300 AA30S05
ODS-AM 3 120 AM12S03
5 AM12S05
ODS-AQ 3 120 AQ12S03
5 AQ12S05
C8 5 120 OC12S05
5 300 OC30S05
C4 5 120 BU12S05
5 300 BU30S05
TMS 5 120 TM12S05
Ph 5 120 PH12S05
CN 5 120 CN12S05
5 300 CN30S05
SIL 5 60 SL06S05
5 120 SL12S05
NH2 5 120 NH12S05

Bulk packing materials (10-50 μm)

Packing material Particle size (μm) Pore size (Å) Product code
ODS-A-HG 10 120 AAG12S11
15 AAG12S16
20 AAG12S21
50 AAG12S50
ODS-AQ-HG 10 120 AQG12S11
15 AQG12S16
20 AQG12S21
50 AQG12S50
SIL-HG 10 120 SLG12S11
15 SLG12S16
20 SLG12S21
50 SLG12S50

For flash chromatography (irregular, 50 μm)

Packing material Product code
SIL SLK08I52
NH2 NHK08I52
Diol DLK08I52
ODS AAK08I52

For flash chromatography (spherical, 25 μm)

Packing material Product code
SIL SLF08S25
NH2 NHF08S25
Diol DLF08S25
ODS AAF08S25

* Prease inquiry Price.

For open column chromatography (spherical, 75, 150 μm)

Packing material Particle size (μm) Pore size (Å) Product code
ODS-A 75 120 AA12S75
150 AA12SA5
SIL 75 120 SL12S75
150 SL12SA5

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