News, Page 1
July 16, 2026
Making Peptide Purification Green without Forfeiting Productivity.
While green solvents like ethanol and DMC are better for the planet, they typically suffer from lower chromatographic resolution in traditional setups. This has resulted in a trade-off of choosing sustainability, or choosing high yield.
The whitepaper Counter-Current Chromatography Enables Use of Green Solvents for Productive Peptide Purification Processes shows how using Multi-column Counter-current Solvent Gradient Purification (MCSGP) can overcome the inefficiencies of eco-friendly mobile phases.
July 8, 2026
Optimizing Liquid Chromatography for Vitamin Analysis
Vitamins play a critical role in human health, serving as precursors to vital coenzymes, supporting metabolic pathways, and offering widespread benefits across the pharmaceutical, nutraceutical, and cosmetic industries. However, analyzing water-soluble vitamins such as the B-complex group and Vitamin C, presents unique challenges for analytical chemists.
June 18, 2026
Happy Retirement, John!
Today, we are celebrating John Heffernan, who is officially stepping into retirement after 16 years with YMC America.
John’s journey with us actually began back when we were known as Integrated Process Technologies, long before we transitioned to YMC America. Over the years, John has worn many hats, from Project Manager to Estimating Manager, Engineering Manager, and ultimately Director of Business Development.
June 2, 2026
Chromatography of Biotherapeuticals – Analyzing and Purifying Peptides and Oligonucleotides
This webinar will highlight how advanced ultra-high-performance liquid chromatography (UHPLC) strategies, carefully selected stationary phases, and bioinert hardware can significantly improve the analysis and purification of peptides and oligonucleotides.
May 21, 2026
Breaking Down mRNA Capping Efficiency with High-Resolution IP-RP LC
Evaluating 5' capping efficiency is a critical quality attribute in therapeutic mRNA manufacturing, directly impacting translation efficiency and transcript stability. However, separating structurally similar capped, partially capped, and uncapped species differing by just a single nucleotide remains a significant chromatographic challenge.
May 7, 2026
Revolutionizing CRISPR Applications: High-Resolution sgRNA Analysis
Ensuring the quality of single guide RNA (sgRNA) is a major hurdle in CRISPR-Cas genome editing. Because these molecules are large (~100mer) and prone to complex secondary structures, separating them from nearly identical impurities requires precision. Our latest application note
April 23, 2026
Eliminating False Positives in PFOS Analysis: The Power of Methanol-Free Separation
Accurate determination of 𝗽𝗲𝗿𝗳𝗹𝘂𝗼𝗿𝗼𝗼𝗰𝘁𝗮𝗻𝗲𝘀𝘂𝗹𝗳𝗼𝗻𝗶𝗰 𝗮𝗰𝗶𝗱 (𝗣𝗙𝗢𝗦) in food samples is challenging due to bile acid–related compounds (e.g., taurocholic acid isomers). These species can produce the same SRM transition (m/z 499→80) as PFOS, leading to potential false positives without adequate chromatographic separation.
April 21, 2026
Using Volunteer Day to help Build Affordable Housing
We are incredibly proud to share how Victor Mansfield recently used his corporate Volunteer Day to make a life-changing difference in the Dominican Republic.
April 14, 2026
Novel Approach for Differentiating mRNA Fingerprints
𝗡𝗲𝘄 𝗕𝗿𝗲𝗮𝗸𝘁𝗵𝗿𝗼𝘂𝗴𝗵 𝗶𝗻 𝗺𝗡𝗥𝗔 𝗙𝗶𝗻𝗴𝗲𝗿𝗽𝗿𝗶𝗻𝘁𝗶𝗻𝗴: 𝗜𝗣𝗔𝗫 𝘅 𝗜𝗣-𝗥𝗣 𝟮𝗗-𝗟𝗖
Confirming mRNA sequences quickly and reliably is no longer a bottleneck. While traditional sequencing or LC-HRMS workflows are often labor-intensive, a 𝐭𝐰𝐨-𝐝𝐢𝐦𝐞𝐧𝐬𝐢𝐨𝐧𝐚𝐥 𝐥𝐢𝐪𝐮𝐢𝐝 𝐜𝐡𝐫𝐨𝐦𝐚𝐭𝐨𝐠𝐫𝐚𝐩𝐡𝐲 (𝟐𝐃-𝐋𝐂) approach is simplifying comprehensive mRNA characterization.
March 24, 2026
Revolutionizing Peptide Purification: A Blueprint for MCSGP Process Validation
The shift from batch to continuous manufacturing is a requirement in many biopharma applications, but regulatory compliance, specifically Process Validation, often remains a hurdle.
March 11, 2026
We are hiring!
We are growing and we're hiring across all functions!
It takes a diverse and skilled team to do what we do, from the initial engineering concept, to the final high-polish finish, to the regional sales champions, and step in between that drives us forward.
January 20, 2026
Join Us at Pittcon 2026
March 9-11, 2026 in San Antonio, TX
