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SemiPrep/Prep: YMC-Pack Pro C18

Ultra-pure Silica-based C18

The YMC Pro Family is based on a silica with an extremely low metal content.  Low metal content suppresses polar interactions, as metal impurities cause silanol groups to become more acidic.  This ensures YMC Pro Family phases provide excellent resolution for a wide range of compounds, especially basic pharmaceuticals.  To minimize the unwanted interactions between residual silanols and the sample molecules that are responsible for asymmetric peaks, YMC utilizes a proprietary, highly effective endcapping process.  Important for every chromatographer: YMC ensures that the physical properties, such as particle size, pore size, and metal content, are extremely reproducible from lot to lot.


YMC-Pack Pro C18: Features & Benefits

Base Material: Ultra-pure Silica
Stationary Phase: C18 (USP L1)
Particle Size: 3µm, 5µm, 10µm
Pore Size: 120Å
Carbon Load: 16%
Bonding: Monomeric
Endcapping: Yes
pH Range: 2-8

YMC-Pack Pro C18 columns start with a tightly controlled, highly purified silica gel, followed by a high-coverage C18 bonding, and finish with a unique endcapping procedure utilizing Lewis acid/Lewis base chemistry.  Together, these features provide unequaled separations with sharp and symmetrical peaks for all types of organic molecules, especially basic pharmaceuticals and chelating compounds.

  • High performance, reproducible, reliable columns designed for the most demanding HPLC separations
  • Made with lightly inert, ultra-pure, pH neutral silica
  • Extremely rigorous physical and chemical specifications
  • Novel Lewis acid/Lewis base endcapping
  • Very high efficiency columns, typically 100,000 to 120,000 plates/meter for 5µm and 130,000 to – 150,000 plates/meter for 3µm packings
  • Continues YMC’s proven lot-to-lot and column-to-column reproducibility.

Product List

Product Table

Please select the desired particle size to view a list of products.


Particle Size Pore Size Column I.D. (mm) Column Length (mm) Endfittings Part Number PriceQuantity
3µm120Å10.0100 Standard ThreadedAS12S03-1010WT $1,303.00
3µm120Å10.0 150Standard Threaded AS12S03-1510WT $1,820.00


Particle Size Pore Size Column I.D. (mm) Column Length (mm) Endfittings Part Number PriceQuantity
5µm120Å10.0 150 Standard Threaded AS12S05-1510WT $1,284.00
5µm120Å10.0 250Standard Threaded AS12S05-2510WT $1,810.00
5µm120Å 20.0 50 Actus AS12S05-0520WX $1,679.00
5µm120Å 20.0 100 Standard Threaded AS12S05-1020WT $2,404.00
5µm120Å 20.0 100 Actus AS12S05-1020WX $2,801.00
5µm120Å 20.0 150 Standard Threaded AS12S05-1520WT $3,204.00
5µm120Å 20.0 150 Actus AS12S05-1520WX $3,299.00
5µm120Å 20.0 250Standard Threaded AS12S05-2520WT $4,390.00
5µm120Å 20.0 250 Actus AS12S05-2520WX $3,600.00
5µm120Å 30.050 Actus AS12S05-0530WX $3,735.00
5µm120Å 30.0 75 Standard Threaded AS12S05-L530WT $4,053.00
5µm120Å 30.0 75 Actus AS12S05-L530WX $4,201.00
5µm120Å 30.0 100 Standard Threaded AS12S05-1030WT $5,431.00
5µm120Å 30.0 100 Actus AS12S05-1030WX $4,902.00
5µm120Å 30.0 150 Standard Threaded AS12S05-1530WT $9,065.00
5µm120Å 30.0 150 Actus AS12S05-1530WX $7,500.00
5µm120Å 30.0 250 Actus AS12S05-2530WX $11,300.00

For information about YMC Actus technology, please click here.


Particle Size Pore Size Column I.D. (mm) Column Length (mm) Endfittings Part Number PriceQuantity
10µm120Å20.0 100 Standard Threaded AS12S11-1020WT $2,281.00
10µm120Å20.0 150 Standard Threaded AS12S11-1520WT $2,556.00
10µm120Å20.0 250 Standard Threaded AS12S11-2520WT $3,241.00
10µm120Å20.0 500Standard Threaded AS12S11-5020WT $7,132.00
10µm120Å 30.0 150 Standard Threaded AS12S11-1530WT $7,561.00
10µm120Å 30.0 250 Standard Threaded AS12S11-2530WT $11,262.00
10µm120Å 30.0 500Standard Threaded AS12S11-5030WT $17,831.00
10µm120Å 50.0 250 Flanged, 1/8" Connector, 1000psi AS12S11-2551DR $16,534.00
10µm120Å 50.0 500 Flanged, 1/8" Connector, 1000psi AS12S11-5051DR $27,557.00

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