Skip to main content
978-487-1100

The YMC Prep Story

Over the years, YMC success stories for Prep LC results have been told over and over again. We are proud of our end-to-end solutions for LC method development and scale-up.

Our solutions for prep embrace every chemistry mode we offer: reversed-phase, IEX, normal phase, SEC, chiral, HIC, and HILIC.

YMC doesn’t stop at just stationary phase chemistry. YMC offers a comprehensive selection of glass columns, screening kits, analytical columns, semi-prep columns, axial compression columns, and pilot-scale columns.

Beyond chemistry and column scale, YMC delivers a complete range of liquid chromatography process equipment — combining the technology strengths of YMC, ChromaCon, and YMC Process Technologies (formerly LEWA-Nikkiso), including MCSGP (Multi-column Counter-current Solvent Gradient Purification).

Get to know YMC Prep! Begin right here on our website.

Posted on December 21, 2020.

Related Posts

May 21, 2026

Breaking Down mRNA Capping Efficiency with High-Resolution IP-RP LC

Evaluating 5' capping efficiency is a critical quality attribute in therapeutic mRNA manufacturing, directly impacting translation efficiency and transcript stability. However, separating structurally similar capped, partially capped, and uncapped species differing by just a single nucleotide remains a significant chromatographic challenge.
Read More

May 7, 2026

Revolutionizing CRISPR Applications: High-Resolution sgRNA Analysis

Ensuring the quality of single guide RNA (sgRNA) is a major hurdle in CRISPR-Cas genome editing. Because these molecules are large (~100mer) and prone to complex secondary structures, separating them from nearly identical impurities requires precision. Our latest application note
Read More

April 23, 2026

Eliminating False Positives in PFOS Analysis: The Power of Methanol-Free Separation

Accurate determination of 𝗽𝗲𝗿𝗳𝗹𝘂𝗼𝗿𝗼𝗼𝗰𝘁𝗮𝗻𝗲𝘀𝘂𝗹𝗳𝗼𝗻𝗶𝗰 𝗮𝗰𝗶𝗱 (𝗣𝗙𝗢𝗦) in food samples is challenging due to bile acid–related compounds (e.g., taurocholic acid isomers). These species can produce the same SRM transition (m/z 499→80) as PFOS, leading to potential false positives without adequate chromatographic separation.
Read More

Designed and developed by